Sprevive® is the very first naturally produced, high-purity, full-dose, spermidine formulation with Generally Regarded as Safe (GRAS) recognition in the USA, determined by an independent Expert Panel.
Spermidine has been extensively studied by modern science for its role in mediating autophagy—a natural process that helps to clear out damaged cells and which is reported to decline with age. Cellular autophagy is crucial to support cellular health and promote healthy aging. Extensive research indicates that the benefits of Spermidine extend beyond autophagy. Evidence suggests that it also modulates inflammation and lipid metabolism, promoting cardiovascular health, fighting anti-oxidative stress and most importantly, improving gut-health as a postbiotic.
Sprevive® has been tested in human clinical trials and developed using a patented natural fermentation process.
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Is a naturally occurring nutrient produced in your gut and found in our diet, known for inducing autophagy. Sprevive® is sustainably produced pure spermidine with no gluten, allergens, or contaminants.
Yes. Chrysea has carried out a randomised placebo-controlled clinical study and a pharmacokinetic and safety clinical study in humans, using 20 mg and 40 mg pure dosages of spermidine, where its metabolism, safety and tolerability were rigorously studied.
Yes. Results from own clinical studies in humans, allowed Chrysea to obtain a Generally Recognised as Safe, (GRAS) Determination by an undependent Expert Panel in the United States of America. Chrysea is pursuing Novel Food status in Europe via the European Food and Safety Authority (EFSA) and a Safety Assessment by the Food Standards Agency in the United Kingdom.
Fermentation is a natural sustainable process used to produce bread, beer, yogurt, wine, and many other ingredients and foods. Using only water and sugars to make products exactly the same as natural origin, it removes the need to use large volumes of plant extracts or complex chemical synthesis processes.
Yes, whilst numerous existing studies have already highlighted spermidine’s health benefits, Chrysea is exploring new and unique avenues in this field. Our team is pioneering research that, for the first time, quantifies the median dietary intakes of spermidine in the United States population as well as studying the associations between spermidine intake levels and biomarkers of health. This innovative work not only sets us apart but also deepens the understanding of spermidine’s role in nutrition and health.